This paper integrates service design into efficiency management and system innovation, and proposes a design process method for enterprises to work efficiently during the prevention against COVID-19. Combined with the AHP, it sorts the importance of the stakeholders and efficiency management touchpoints in the enterprise service system, builds a stakeholder map, and then visualizes the efficient office processes through the service blueprint. Aiming at the current management situation of cross-regional and multi-office co-existence of enterprises in the epidemic outbreak, this paper proposes methods such as target management, task decomposition,and timely feedback to improve the office efficiency of enterprises. Taking the office model of Joya National Industrial Design Center as a case for demonstration, it emphasizes that the core of service design is human-centered. Through the optimization of the corporate office system, an efficient office process is finally formed, which provides effective solutions for service design innovation in the direction of enterprise management.