The public crisis is a huge dilemma facing human beings at any time. During the crisis, the rapid spread of various scientific popular science posters has proved time and time again that it has shown a powerful force in responding to the crisis. In the new era, people are facing various public crises that are constantly happening. Traditional science-based public welfare posters have gradually changed from their original emotional appeals to more accurate information transmission, which is also related to people's times. With the development of the times, the creative ideas of public welfare posters are not limited to the imagination of designers.The power of design further confirms the powerful creativity generated by the combination of science and art. The starting point of this article is to re-examine the creation of traditional public welfare posters from the perspective of the new era, big data, creative methods, paths, and innovation,with a view on the public welfare elevation design level of science popular public welfare posters and their future development laws to finding more possibilities.