Based on the intersection of history, the paper intends to summarize the artistic expression methods of exhibition design of centennial major themes of Communist Party of China and play a greater role in the new journey to achieve the second Centenary Goal. By sorting out the major themes that have occurred in the past hundred years, and selecting five representative exhibition halls and memorial sites for investigation, then analyze the investigation date by history, narratology, design and other methods, and summarize the characteristics and regular patterns of exhibition art design. Through analysis and research, the principles of topic selection planning, text writing, cultural relics and exhibits and other major historical themes content design will be obtained. In the aspect of formal design, the basic points and key elements of narrative display design are sorted out, and new initiatives for the digital and intelligent development trend of museums in the information age are explored. The principles of content design of the exhibition on major themes of the centenary Party histories can play a guiding role in constructing the exhibition hall and planning on the subject of patriotism education in the future. The research result of major themes display, such as visual art language, digital integration and innovation are of exemplary significance in the display design of major themes in the next century.