To address the issue that elderly population is not considered in the current interface color selection, the work aims to rely on the biophilic theory to study interface color design strategies that are more suitable for the elderly population. Firstly, the physical and mental characteristics of the elderly population are analyzed from the need perspective, and combined with the health care mechanisms of biophilic theory, an interface color design strategy for the elderly population based on the biophilic theory is constructed. By constructing a rich and natural sample color library, formulating a time-aware dynamic color strategy, and combining biological characteristics, positive color associations are created for the elderly population, which can effectively leverage human's pro-biological instincts, constructing a better color interface for the elderly population.