Focusing on the construction and improvement of comprehensive courses under the background of new liberal arts, this paper points out that as a cross domain comprehensive design practice course, students should focus on finding problems, analyzing problems and solving problems from practical experience. According to the different social and design cognition of students in each learning stage, students are divided into following three learning stages: low, medium and high. By refining the method of deconstructing design practice courses, the courses are decomposed according to the characteristics of the discipline and the learning needs of students in each learning stage, and the courses are constructed in sections, so as to become the teaching method and execution order of design practice courses. This paper discusses the necessity of segmented construction of design practice courses from two aspects: conforming to the characteristics of the discipline and the changes of students' cognition and needs, thereby fully applying it in the practical teaching of the three learning stages. Furthermore, by deeply cultivating the changes of students' learning needs and refining the course content, this paper explores the method of segmented construction of design practice courses, and explores a new way for the cultivation of new liberal arts talents serving the design majors.